3',4'-Methylenedioxy-α-pyrrolidinobutiophenone

Тема в разделе "Euphoric substances and stimulants", создана пользователем Charles Darwin, 3/5/14.

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    Charles Darwin

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    3',4'-Methylenedioxy-α-pyrrolidinobutyrophenone(MDPBP)

    is a
    compound developed in the 1960s, which has been reported as a novel
    , often sold under the name "NRG-1" as a mixture with other
    derivatives, including
    ,
    ,
    and
    .

    The main metabolic steps are thought to be demethylenation followed by methylation of one hydroxy group, aromatic and side chain hydroxylation, oxidation of the pyrrolidine ring to the corresponding lactam as well as ring opening to the corresponding carboxylic acid. CYP2C19 and CYP2D6 have been identified as the isoenzymes mainly responsible for demethylenation.
     
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    Charles Darwin, 3/5/14
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